For Pregnant Women With Cancer, Chemo Possible

Researchers have encouraging news for women who find themselves in a very frightening situation: having cancer while pregnant. Studies suggest that these women can be treated almost the same as other cancer patients are, with minimal risk to the fetus.

Only about 1 in 1,000 pregnant women face this dilemma, but doctors fear that more will because the risk of cancer rises with age, and more women are delaying having children until they’re older.

Doctors have long worried about how to balance treating a pregnant woman with cancer and the need to protect her fetus from the effects of toxic cancer drugs and radiation treatments, and whether it is safe to continue a pregnancy in certain situations. A series of papers in the journals Lancet and Lancet Oncology published Friday make several key contributions: [Read more...]

Breastfeeding Can Reduce Risk Of Childhood Obesity

Children of diabetic pregnancies have a greater risk of childhood obesity, but new research from the Colorado School of Public Health shows breastfeeding can reduce this threat.

Epidemiologist Tessa Crume, Ph.D., MSPH, and fellow researchers tracked 94 children of diabetic pregnancies and 399 of non-diabetic pregnancies from birth to age 13. They evaluated the influence of breastfeeding on the growth of body mass index (BMI), an indicator of childhood obesity.

“There are critical perinatal periods for defining obesity risk, pregnancy and early infant life,” Crume said. “We looked at children exposed to over-nutrition in utero due to a diabetic pregnancy to determine if early life nutrition could alter their risk of childhood obesity.” [Read more...]

Morbidly Obese Woman Rotted In Chair

Priscilla Frieberger, 61, spent the last three weeks of her life literally stuck to a brown cloth recliner, in a horribly cluttered home that she shared with her sister, an Indiana prosecutor says.

“She was morbidly obese, got sick and couldn’t get out of her chair — and her sister left her there like that for three weeks,” Dearborn County prosecutor Aaron Negangard said. “The paramedics couldn’t get her removed from the chair because she was stuck — she was rotting, basically, in the chair.”

Frieberger’s sister, Vickie Holdcraft, was indicted Friday on charges of reckless homicide, three counts of neglect and two counts of perjury for allegedly making false statements to a grand jury, Negangard said. The charges stem from Frieberger’s death on Oct. 2; as of late Friday, Holdcraft had not yet been arrested, the Dearborn County Sheriff’s Office said. [Read more...]

Why Obesity May Not Be All Bad

It’s well known that being fat can be a fast track to diabetes and heart disease.

But now Sydney doctors say some obese folk are less at risk from the two potentially deadly illnesses than others – and they’ve launched a new study to find out why.

Experts at the Garvan Institute, the medical research facility at Sydney’s St Vincent’s Hospital, say there are “healthy obese people” whose insulin works just as well as in someone who is lean.

These same people also appear to be less at risk of dying from cardiovascular disease. [Read more...]

Obesity Could Be Infectious

We’ve heard obesity can be “spread” between friends when we copy each other’s eating habits, but a new study in mice suggests obesity could actually be infectious.

That’s right, infectious. As in, something you can catch.

In the study, mice engineered to have a particular immune deficiency developed fatty liver disease and got fatter when fed a Western-style diet. But strikingly, when these immune-deficient mice were put in the same cage as healthy mice, the healthy mice started to come down with symptoms of liver disease, and also got fatter. [Read more...]

Rare Kidney Disease Shows How Salt, Potassium Levels Are Moderated

High blood pressure (hypertension) is a principal risk factor for heart disease and affects 1 billion people. At least half of them are estimated to be salt-sensitive; their blood pressure rises with sodium intake. New research released today shows important aspects of how sodium and potassium are regulated in the kidney.

The work, posted online by Nature, also offers insight on how one form of familial high blood pressure disease is inherited. Nephrology researchers in the School of Medicine at The University of Texas Health Science Center San Antonio are co-authors.

Disease includes high potassium levels, low pH

The study explores the mechanisms of a rare, inherited kidney disease called pseudohypoaldosteronism type II (PHAII). This disease is marked by hypertension, higher-than-normal levels of potassium, and low pH, acidic body fluids. [Read more...]

Genes Which Time Menopause Identified

Researchers have identified 13 new regions of genes, which can help in predicting the onset of menopause.

These genes shed light on the biological pathways involved in reproductive lifespan and will provide insights into conditions connected to menopause, such as breast cancer and heart disease.

Menopause is a major hormonal change that affects most women when they are in their early 50s. The timing of menopause can have a huge impact on fertility, as well as influencing the risk of a range of common diseases such as breast cancer. It has been known for some time that genetic factors influenced the onset of menopause, however until recently very few genes had been identified. [Read more...]